Killing Rats in Toothpaste Tests? The Gov Is Requiring This!

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You use it every day—but did you know that your toothpaste may be tested on rats?

Try making sense of this. The U.S. Food and Drug Administration (FDA) requires tests where up to 200 rats are given cavities. Then, the rats are exposed to the toothpaste over and over before having their heads cut off, placed in a baking pan, and steamed to see how well the product prevents cavities. Killing rats… preventing cavities… struggling to see a connection here. 🤦🤦🤦

There are much, MUCH better ways to do this. Ways that don’t hurt rats, that DO produce human-relevant results, and give you a reason to flash that healthy smile.

Sign below to urge the FDA to let manufacturers readily use an animal-free test method ASAP! 🐀

End Animal Testing for Toothpastes

I urge you to update—without delay—the FDA’s Anticaries Drug Products for Over-the-Counter Human Use Monograph to include the use of the pH cycling method as an accepted alternative to the animal caries test. This non-animal method is well established, extensively evaluated, and supported by a substantial body of data.

The pH cycling method offers greater reliability and human relevance than the currently used animal test, and it aligns with the direction that both the U.S. and global toothpaste industries have moved to over the past 25 years in favor of non-animal methods.

Requiring an animal test for efficacy of fluoridated over-the-counter products is inconsistent with modern science, ethical expectations, and international regulatory practice. It creates a barrier to the use of more human-relevant non-animal methods.

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